AmiGO 2: Term Details for "NEDD8 ligase activity" (GO:0061663)

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Term Information

Accession: GO:0061663
Name: NEDD8 ligase activity
Ontology: molecular_function
Synonyms: E3
Alternate IDs: None
Definition: Catalysis of the transfer of NEDD8 to a substrate protein via the reaction X-NEDD8 + S = X + S-NEDD8, where X is either an E2 or E3 enzyme, the X-NEDD8 linkage is a thioester bond, and the S-NEDD8 linkage is an isopeptide bond between the C-terminal amino acid of NEDD8 and the epsilon-amino group of lysine residues in the substrate. Source: GOC:dph
Comment: None
History: See term history for GO:0061663 at QuickGO
Chem. react.: None
Subset: None
Related: Link to all genes and gene products annotated to NEDD8 ligase activity (excluding "regulates").; Link to all direct and indirect annotations to NEDD8 ligase activity (excluding "regulates").; Link to all direct and indirect annotations download (limited to first 10,000) for NEDD8 ligase activity (excluding "regulates").

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For more information, please see the ontology relation documentation.

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GO:0003824 catalytic activity
GO:0003674 molecular_function
GO:0016740 transferase activity
GO:0016746 acyltransferase activity
GO:0016755 aminoacyltransferase activity
GO:0140096 catalytic activity, acting on a protein
GO:0019787 ubiquitin-like protein transferase activity
GO:0019788 NEDD8 transferase activity
GO:0061659 ubiquitin-like protein ligase activity
GO:0061663 NEDD8 ligase activity

Parents of NEDD8 ligase activity (GO:0061663)

subject	relation	object
NEDD8 ligase activity	is_a	NEDD8 transferase activity (GO:0019788)
NEDD8 ligase activity	is_a	ubiquitin-like protein ligase activity (GO:0061659)

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EC: 2.3.2.32