AmiGO 2: Term Details for "ruffle assembly" (GO:0097178)

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Term Information

Accession: GO:0097178
Name: ruffle assembly
Ontology: biological_process
Synonyms: membrane ruffle formation, membrane ruffling
Alternate IDs: None
Definition: The aggregation, arrangement and bonding together of a set of components to form a ruffle, a projection at the leading edge of a crawling cell; the protrusions are supported by a microfilament meshwork. The formation of ruffles (also called membrane ruffling) is thought to be controlled by a group of enzymes known as Rho GTPases, specifically RhoA, Rac1 and cdc42. Source: PMID:12556481, GOC:yaf, Wikipedia:Membrane_ruffling
Comment: None
History: See term history for GO:0097178 at QuickGO
Chem. react.: None
Subset: None
Related: Link to all genes and gene products annotated to ruffle assembly (excluding "regulates").; Link to all direct and indirect annotations to ruffle assembly (excluding "regulates").; Link to all direct and indirect annotations download (limited to first 10,000) for ruffle assembly (excluding "regulates").

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For more information, please see the ontology relation documentation.

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GO:0008150 biological_process
GO:0009987 cellular process
GO:0071840 cellular component organization or biogenesis
GO:0044085 cellular component biogenesis
GO:0016043 cellular component organization
GO:0030030 cell projection organization
GO:0022607 cellular component assembly
GO:0030031 cell projection assembly
GO:0120036 plasma membrane bounded cell projection organization
GO:0120031 plasma membrane bounded cell projection assembly
GO:0031529 ruffle organization
GO:0097178 ruffle assembly
GO:1900028 negative regulation of ruffle assembly
GO:1900029 positive regulation of ruffle assembly
GO:1900027 regulation of ruffle assembly

Parents of ruffle assembly (GO:0097178)

subject	relation	object
ruffle assembly	is_a	plasma membrane bounded cell projection assembly (GO:0120031)
ruffle assembly	is_a	ruffle organization (GO:0031529)
ruffle assembly	RO:0002588	ruffle (GO:0001726)
ruffle assembly	RO:0002162	cellular organisms (NCBITaxon:131567)

Children of ruffle assembly (GO:0097178)

subject	relation	object
regulation of ruffle assembly (GO:1900027)	RO:0002211	ruffle assembly
negative regulation of ruffle assembly (GO:1900028)	RO:0002212	ruffle assembly
positive regulation of ruffle assembly (GO:1900029)	RO:0002213	ruffle assembly

Wikipedia: Membrane_ruffling