Term Information

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Accession
GO:1990712
Name
HFE-transferrin receptor complex
Ontology
cellular_component
Synonyms
None
Alternate IDs
None
Definition
A protein complex containing at least HFE and a transferrin receptor (either TFR1/TFRC or TFR2), proposed to play a role in the sensing of transferrin-bound Fe (Fe2-Tf) on the plasma membrane to regulate hepcidin transcription. Source: GOC:kom, GOC:BHF, PMID:25147378
Comment
None
History
See term history for GO:1990712 at QuickGO
Chem. react.
None
Subset
None
Include "regulates"
For more information, please see the ontology relation documentation.

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Parents of HFE-transferrin receptor complex (GO:1990712)
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HFE-transferrin receptor complex [is_a relation] is_a  plasma membrane signaling receptor complex (GO:0098802)
HFE-transferrin receptor complex [RO:0002216 relation] RO:0002216  intracellular iron ion homeostasis (GO:0006879)

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None.