3347-22-6
3347-22-6 结构式
基本信息
二氰蒽醌
二噻农
2,3-二腈基-1,4-二硫代蒽醌
5,10-二氢-5,10-二氧萘基[2,3-B]-1,4-二硫杂环-2,3-二腈
75%二氰蒽醌可湿性粉剂
二氰蒽醌悬浮剂
2,3-DICYANO-1,4-DITHIAANTRAQUINONE
5,10-DIHYDRO-5,10-DIOXONAPHTHO-[2,3-B]-1,4-DITHIIN-2,3-DICARBONITRILE
5,10-DIHYDRO-5,10-DIOXONAPHTHO[2,3-B]-P-DITHIIN-2,3-DICARBONITRILE
5,10-DIOXO-5,10-DIHYDRO-NAPHTHO[2,3-B][1,4]DITHIINE-2,3-DICARBONITRILE
AKOS NCG1-0094
AKTUAN
CLUSTER
DELAN
DELAN-COL
DELAN(R)
Dicyano-1,4-dithia-anthraquinone
dithiaanthraquinone-2,3-dinitrile
DITHIANON
1,4-dithiaanthraquinone-2,3-dicarbonitrile
1,4-dithiaanthraquinone-2,3-dinitrile
2,3-dicarbonitrilo-1,4-diathiaanthrachinon
2,3-dinitrilo-1,4-dithia-9,10-anthraquinone
2,3-dinitrilo-1,4-dithiaanthraquinone
2,3-dinitrilo-1,4-dithia-anthraquinone
物理化学性质
安全数据
常见问题列表
二氰蒽醌(dithianon)，试验代号 BAS216F、CL37114、CME107、IT-931、MV119A SAG107。商品名称 Agrition、Delan、Ditho、Dock、Fado、Kuki、Minosse、Zot。其他名称二噻农，是由BASF公司开发的杀菌剂。
二氰蒽醌纯品为深棕色结晶状固体，具有铜的光泽(工业品浅棕色)，熔点 215~216℃；蒸气压2.7X10mPa。分配系数 KowlgP=3.2，Henry常数5.71X10Pam/mol(计算值) 相对密度1.576kg/m(20C)。水中溶解度(pH 7,20C):0.14mg/L。有机溶剂溶解度(g/L. 20C):甲苯8，氯仿12，丙酮 10;微溶于甲醇和二氯甲烷。浓酸、碱性介质中及长时间加热会 分解，DTs,12.2h(pH7,25C)。稳定存在至80℃。水溶液(0.1mg/L)暴露于人造光下时 DT50 19h。闪点>300℃。
二氰蒽醌以蔡为原料，经如下反应即制得目的物。
大鼠急性经口LD50>300mg/kg，大鼠急性经皮 LD50>2000mg/kg。对皮肤无刺激对眼严重刺激。雄性大鼠吸入LC50(4h)0.28mg/L空气。NOEL[2y,mg/(kg·d)]:大鼠(2y)1. 狗(ly)1.6，小鼠(1.5y)2.8。ADI0.01mg/kg。无遗传毒性。制剂毒性:轻度急性经口毒性，无 生殖、发育毒性，无致癌性。
Reactive oxygen species (ROS)
Colletotrichum sp.
;
Elsinoe ampelina
;
Plasmopara viticola
;
Phomopsis viticola
When exponentially aerobic growing cells of
S. cerevisiae
are submitted to acute Dithianon treatment they loss cell wall and membrane integrity, dying by necrosis, and this behavior is associated to a depletion of reduced proteic and non-proteic thiol groups. An important increase of cellular reactive oxygen species (ROS) associated to mitochondrial membrane potential modifications on Dithianon treated cells are also detected.
In filamentous fungus, Dithianon inhibits mycelial growth and conidial germination. Studies on Ehrlich ascites carcinoma and yeast cells showed that Dithianon inhibits respiration and fermentation affecting several thiol enzymes of the glycolytic pathway as hexokinase, phosphofructokinase, and glyceraldeyde-3-phosphate dehydrogenase.
Dithianon has in vitro cytotoxic effect and affect cell transforming activity of BLAB/c 3 T3 cells.
The activity of testosterone hydroxylase of liver microsomes derived from male mice is increased when they are treated with acute doses of Dithianon, while in females an inactivating effect is observed.