Levosulpiride
- CAS No.
- 23672-07-3
- Chemical Name:
- Levosulpiride
- Synonyms
- Levosulpride;l-Form;rv-12309;Levopride;levopraid;l-Sulpirid;levosupride;l-Sulpiride;LEVOSULPIRIDE;(S)-(-)-Sulpir
- CBNumber:
- CB4422019
- Molecular Formula:
- C15H23N3O4S
- Molecular Weight:
- 341.43
- MDL Number:
- MFCD00055220
- MOL File:
- 23672-07-3.mol
- MSDS File:
- SDS
Melting point | 183-186 °C(lit.) |
---|---|
Density | 1.236±0.06 g/cm3(Predicted) |
storage temp. | 2-8°C |
solubility | DMF (Slightly), DMSO (Slightly), Methanol (Slightly) |
pka | 9.98±0.60(Predicted) |
form | Solid |
color | White to Off-White |
Merck | 14,8989 |
InChIKey | BGRJTUBHPOOWDU-NSHDSACASA-N |
CAS DataBase Reference | 23672-07-3(CAS DataBase Reference) |
FDA UNII | JTG7R315LK |
ATC code | N05AL07 |
UNSPSC Code | 41116107 |
NACRES | NA.77 |
Levosulpiride price More Price(31)
Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|---|
Sigma-Aldrich | S7771 | (S)-(?)-Sulpiride ≥98% (titration) | 23672-07-3 | 5g | $96.1 | 2024-03-01 | Buy |
Sigma-Aldrich | 34002 | (S)-(−)-Sulpiride VETRANAL?, analytical standard | 23672-07-3 | 100mg | $145 | 2024-03-01 | Buy |
Sigma-Aldrich | 5.05626 | (S)-Sulpiride - CAS 23672-07-3 - Calbiochem | 23672-07-3 | 100mg | $82.2 | 2022-05-15 | Buy |
TCI Chemical | I0821 | (S)-(-)-Sulpiride >98.0%(HPLC)(T) | 23672-07-3 | 5g | $108 | 2024-03-01 | Buy |
TCI Chemical | I0821 | (S)-(-)-Sulpiride >98.0%(HPLC)(T) | 23672-07-3 | 25g | $271 | 2024-03-01 | Buy |
Levosulpiride Chemical Properties,Uses,Production
Chemical Properties
White Solid
Uses
(S)-(?)-Sulpiride was used to study the effect of dopamine D2 receptor function on activation of KCNQ potassium channels10 and on depression-like behavior in ovariectomized female rats.11
Uses
dopamine receptor antagonists
Uses
Dopamine D2 and D3-receptor antagonist. Antipsychotic; antidepressant; antiemetic.
Definition
ChEBI: An optically active form of sulpiride having (S)-configuration. The active enantiomer of the racemic drug sulpiride. Selective D2-like dopamine antagonist (Ki values are ~ 0.015. ~ 0.013, 1, ~ 45 and ~ 77 muM at D2, D3, D4, 1 and D5 receptors respectively).
General Description
(S)-(?)-Sulpiride is a levorotatory enantiomer of sulpiride, which shows greater central antidopaminergic activity, antiemetic and antidyspeptic effects. It is also used as a therapeutic drug for the treatment of depression and somatoform disorders.
Biological Activity
Active enantiomer. Selective D 2 -like dopamine antagonist (K i values are ~ 0.015. ~ 0.013, 1, ~ 45 and ~ 77 μ M at D 2 , D 3 , D 4 , D 1 and D 5 receptors respectively).
Biochem/physiol Actions
(S)-(?)-Sulpiride or Levosulpiride blocks the inhibitory enteric D2 receptors (neuronal and muscular). It has prokinetic activity and is effective in the treatment of functional dyspepsia and gastroparesis in insulin-dependent diabetes mellitus patients.7,8 Since dopamine controls human sexual function, (S)-(?)-Sulpiride is reportedly effective in treatment of erectile dysfunctions.9
storage
Room temperature
Levosulpiride Preparation Products And Raw materials
Supplier | Tel | Country | ProdList | Advantage | |
---|---|---|---|---|---|
Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 | info@tianfuchem.com | China | 21629 | 55 |
Hubei xin bonus chemical co. LTD | 86-13657291602 | linda@hubeijusheng.com | CHINA | 22963 | 58 |
Chongqing Chemdad Co., Ltd | +86-023-6139-8061 +86-86-13650506873 | sales@chemdad.com | China | 39894 | 58 |
CONIER CHEM AND PHARMA LIMITED | +8618523575427 | sales@conier.com | China | 49732 | 58 |
career henan chemical co | +86-0371-86658258 +8613203830695 | factory@coreychem.com | China | 29808 | 58 |
SIMAGCHEM CORP | +86-13806087780 | sale@simagchem.com | China | 17365 | 58 |
TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 | marketing@targetmol.com | United States | 32159 | 58 |
Jinan Qinmu Fine Chemical Co.,Ltd. | +8618660799346 | sales@qinmuchem.com | China | 1009 | 58 |
Hefei TNJ Chemical Industry Co.,Ltd. | +86-0551-65418671 +8618949823763 | sales@tnjchem.com | China | 34563 | 58 |
Dorne Chemical Technology co. LTD | +86-86-13583358881 +8618560316533 | Ethan@dornechem.com | China | 3084 | 58 |
View Lastest Price from Levosulpiride manufacturers
Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
---|---|---|---|---|---|---|---|---|
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2024-11-19 | Levosulpiride
23672-07-3
|
US $50.00 / mg | 99.93% | 10g | TargetMol Chemicals Inc. | ||
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2024-03-16 | Levosulpiride
23672-07-3
|
US $35.00-25.00 / kg | 1kg | 99.8% | 200tons/year | Sigma Audley | |
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2024-01-16 | Levosulpiride
23672-07-3
|
US $45.00-35.00 / kg | 1kg | 99.8% | 200tons/year | Sigma Audley |
-
- Levosulpiride
23672-07-3
- US $50.00 / mg
- 99.93%
- TargetMol Chemicals Inc.
-
- Levosulpiride
23672-07-3
- US $35.00-25.00 / kg
- 99.8%
- Sigma Audley
-
- Levosulpiride
23672-07-3
- US $45.00-35.00 / kg
- 99.8%
- Sigma Audley