Welcome to LookChem.com Sign In|Join Free

CAS

  • or

1350743-83-7

4-({[5-(2-methylphenyl)-1,3,4-oxadiazol-2-yl]methyl}amino)-1,5-dimethyl-2-phenyl-1,2-dihydro-3H-pyrazol-3-one is a chemical with a specific purpose. Lookchem provides you with multiple data and supplier information of this chemical.

1350743-83-7 Suppliers

Post Buying Request

Recommended suppliersmore

  • Product
  • FOB Price
  • Min.Order
  • Supply Ability
  • Supplier
  • Contact Supplier
  • 1350743-83-7 Structure

  • Basic information

    1. Product Name: 4-({[5-(2-methylphenyl)-1,3,4-oxadiazol-2-yl]methyl}amino)-1,5-dimethyl-2-phenyl-1,2-dihydro-3H-pyrazol-3-one
    2. Synonyms: 4-({[5-(2-methylphenyl)-1,3,4-oxadiazol-2-yl]methyl}amino)-1,5-dimethyl-2-phenyl-1,2-dihydro-3H-pyrazol-3-one
    3. CAS NO:1350743-83-7
    4. Molecular Formula:
    5. Molecular Weight: 375.43
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 1350743-83-7.mol

  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: N/A
    3. Flash Point: N/A
    4. Appearance: N/A
    5. Density: N/A
    6. Refractive Index: N/A
    7. Storage Temp.: N/A
    8. Solubility: N/A
    9. CAS DataBase Reference: 4-({[5-(2-methylphenyl)-1,3,4-oxadiazol-2-yl]methyl}amino)-1,5-dimethyl-2-phenyl-1,2-dihydro-3H-pyrazol-3-one(CAS DataBase Reference)
    10. NIST Chemistry Reference: 4-({[5-(2-methylphenyl)-1,3,4-oxadiazol-2-yl]methyl}amino)-1,5-dimethyl-2-phenyl-1,2-dihydro-3H-pyrazol-3-one(1350743-83-7)
    11. EPA Substance Registry System: 4-({[5-(2-methylphenyl)-1,3,4-oxadiazol-2-yl]methyl}amino)-1,5-dimethyl-2-phenyl-1,2-dihydro-3H-pyrazol-3-one(1350743-83-7)

  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 1350743-83-7(Hazardous Substances Data)

1350743-83-7 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 1350743-83-7 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,3,5,0,7,4 and 3 respectively; the second part has 2 digits, 8 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 1350743-83:
(9*1)+(8*3)+(7*5)+(6*0)+(5*7)+(4*4)+(3*3)+(2*8)+(1*3)=147
147 % 10 = 7
So 1350743-83-7 is a valid CAS Registry Number.

1350743-83-7Downstream Products

1350743-83-7Relevant articles and documents

Molecular properties prediction and synthesis of novel 1,3,4-oxadiazole analogues as potent antimicrobial and antitubercular agents

Ahsan, Mohamed Jawed,Samy, Jeyabalan Govinda,Khalilullah, Habibullah,Nomani, Md. Shivli,Saraswat, Pankaj,Gaur, Ramakant,Singh, Abhimanyu

, p. 7246 - 7250 (2012/02/04)

In the present investigation, a series of 1,5-dimethyl-2-phenyl-4-{[(5- aryl-1,3,4-oxadiazol-2-yl)methyl]amino}-1,2-dihydro-3H-pyrazol-3-one were subjected to molecular properties prediction, drug-likeness by Molinspiration (Molinspiration, 2008) and MolSoft (MolSoft, 2007) software, lipophilicity and solubility parameters using ALOGPS 2.1 program. The compounds followed the Lipinski 'Rule of five' were synthesized for antimicrobial and antitubercular screening as oral bioavailable drugs/leads. Maximum drug-likeness model score (0.95) was found for compound, 4a. All the synthesized compounds were characterized by IR, NMR and mass spectral analysis followed by antimicrobial and antimycobacterial screening. Among the title compounds, compound 4d showed pronounced activity against Mycobacterium tuberculosis H37Rv and isoniazid resistant M. tuberculosis (INHR-TB) with minimum inhibitory concentrations (MICs) 0.78 μM and 1.52 μM, respectively. The compound, 4a showed maximum activity against all bacterial strains with MIC 4-8 μg/mL comparable to standard drug ciprofloxacin, while the compounds, 4e and 4k showed maximum antifungal activity with MIC 8-16 μg/mL less active than standard drug fluconazole.

Post a RFQ

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

1

What can I do for you?
Get Best Price

Get Best Price for 1350743-83-7