Welcome to LookChem.com Sign In|Join Free

CAS

  • or

19997-53-6

2-(bromomethyl)-2,3-dihydrobenzofuran is a brominated heterocyclic compound derived from 2,3-dihydrobenzofuran, featuring a furan ring fused to a benzene ring with a bromomethyl group attached. This chemical compound is widely utilized in organic synthesis due to its reactivity in various chemical reactions, such as nucleophilic substitution and palladium-catalyzed coupling reactions.

19997-53-6 Suppliers

Post Buying Request

Recommended suppliersmore

  • Product
  • FOB Price
  • Min.Order
  • Supply Ability
  • Supplier
  • Contact Supplier
  • 19997-53-6 Structure

  • Basic information

    1. Product Name: 2-(bromomethyl)-2,3-dihydrobenzofuran
    2. Synonyms: 2-(bromomethyl)-2,3-dihydrobenzofuran
    3. CAS NO:19997-53-6
    4. Molecular Formula: C9H9BrO
    5. Molecular Weight: 213.07116
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 19997-53-6.mol

  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: 279 °C at 760 mmHg
    3. Flash Point: 110.4 °C
    4. Appearance: /
    5. Density: 1.481 g/cm3
    6. Vapor Pressure: 0.00697mmHg at 25°C
    7. Refractive Index: 1.579
    8. Storage Temp.: N/A
    9. Solubility: N/A
    10. CAS DataBase Reference: 2-(bromomethyl)-2,3-dihydrobenzofuran(CAS DataBase Reference)
    11. NIST Chemistry Reference: 2-(bromomethyl)-2,3-dihydrobenzofuran(19997-53-6)
    12. EPA Substance Registry System: 2-(bromomethyl)-2,3-dihydrobenzofuran(19997-53-6)

  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 19997-53-6(Hazardous Substances Data)

19997-53-6 Usage

Uses

Used in Pharmaceutical Industry:
2-(bromomethyl)-2,3-dihydrobenzofuran serves as a valuable precursor for the synthesis of biologically active molecules, contributing to the development of potential pharmaceutical agents. Its unique structure and reactivity facilitate the creation of diverse drug candidates with therapeutic potential.
Used in Agrochemical Industry:
In the agrochemical sector, 2-(bromomethyl)-2,3-dihydrobenzofuran is employed as a building block for the synthesis of various organic compounds with pesticidal or herbicidal properties. Its versatility in chemical reactions allows for the development of novel agrochemicals with improved efficacy and selectivity.
Used in Material Science:
2-(bromomethyl)-2,3-dihydrobenzofuran also finds application in the material science field, where it is used as a component in the synthesis of advanced materials with specific properties. Its incorporation into material structures can lead to the development of new materials with enhanced performance characteristics for various applications.
Overall, 2-(bromomethyl)-2,3-dihydrobenzofuran is a versatile chemical compound with broad applications across different industries, including pharmaceuticals, agrochemicals, and material science, due to its unique structure and reactivity in organic synthesis.

Check Digit Verification of cas no

The CAS Registry Mumber 19997-53-6 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,9,9,9 and 7 respectively; the second part has 2 digits, 5 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 19997-53:
(7*1)+(6*9)+(5*9)+(4*9)+(3*7)+(2*5)+(1*3)=176
176 % 10 = 6
So 19997-53-6 is a valid CAS Registry Number.
InChI:InChI=1/C9H9BrO/c10-6-8-5-7-3-1-2-4-9(7)11-8/h1-4,8H,5-6H2

19997-53-6SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 18, 2017

Revision Date: Aug 18, 2017

1.Identification

1.1 GHS Product identifier

Product name 2-(bromomethyl)-2,3-dihydro-1-benzofuran

1.2 Other means of identification

Product number -
Other names 2-Bromomethyl-2,3-dihydrobenzofuran

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:19997-53-6 SDS

19997-53-6Downstream Products

19997-53-6Relevant articles and documents

Synthesis of monofluorinated C4-building blocks based on methallyl chloride

Haufe, Guenter,Wessel, Ulrich,Schulze, Klaus,Alvernhe, Gerard

, p. 283 - 292 (2007/10/03)

Halofluorination of methallyl chloride using N-halosuccinimides in combination with triethylamine trishydrofluoride (Et3N*3HF) gave in each case more than 98percent of the Markovnikov products and 2percent of the regioisomers in good yield.The formal addition of methanesulfenyl fluoride with the combination of dimethyl(methylthio)sulfonium fluoroborate (DMTSF) and Et3N*3HF gave a 94:6 mixture of both regioisomers.Only small phenylsulfenyl fluorination of methallyl chloride has been observed when treated with N-phenylthiophthalimide (NPTP) and Olah's reagent.With benzenesulfenyl chloride, 1,3-dichloro-2-methyl-2-(phenylthio)propane is formed which on treatment with Olah's reagent at 0 deg C or with Et3N*3HF at 60 deg C rearranges to 1,2-dichloro-2-methyl-3-(phenylthio)propane.Treatment of 1,3-dichloro-2-methyl-2-(phenylthio)propane with silver fluoride in methylene chloride at -30 deg C gave 1-chloro-2-fluoro-2-methyl-3-(phenylthio)propane which was also obtained by reaction of 1-bromo-3-chloro-2-fluoro-2-methylpropane with thiophenolate.Chlorofluorination of methallylphenylthio ether using NCS/Et3N*3HF failed, while corresponding reactions with NBS or NIS and Et3N*3HF gave mainly the bromo- or iodo-fluorides with Markovnikov orientation in 61percent or 35percent yields.Related halofluorinations of methallylphenyl ether gave the halofluorides in good yield.All attempts to obtain chromanes or thiochromanes bearing a 3-fluorine substituent by cyclization of these halofluorinated ethers or thio ethers failed using different Lewis acids.However, the benzyl protected o-allylphenol which was bromofluorinated with NBS/Et3N*3HF in good yield gave on catalytic hydrogenation over Pd/C the 3-fluoro-2H-chromane in nearly quantitative yield. - Keywords: Electrophilic addition; Halofluorination; Sulfenylfluorination; N-Halosuccinimides; Dimethyl(methylthio)sulfonium tetrafluoroborate; Triethylamine trishydrofluoride

Anti-hypertensive compounds and compositions

-

, (2008/06/13)

Compounds of formula (I): STR1 or a pharmaceutically acceptable salt thereof, wherein m is 0 to 3; n is 1 to 5; R1 is hydrogen, or C1-6 alkyl; R2 is hydrogen, C1-4 alkyl, --(CH2)p --NH2 wherein p is 1 to 4, or --NHCOR, wherein R5 is C1-4 alkyl; R3 is hydrogen or C1-6 alkyl; R4 is C1-4 alkyl, C1-4 alkoxy, halogen or CF3 ; and X is CH2 or S. having useful pharmacological activity, compositions containing them, and a process for their preparation.

Post a RFQ

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

1

What can I do for you?
Get Best Price

Get Best Price for 19997-53-6