The bacterium's place in nature / Jan Sapp -- The large-scale structure of the Tree of Life / Norman R. Pace -- The molecular phylogeny of bacteria based on conserved genes / Wolfgang Ludwig and Karl-Heinz Schleifer -- Evolving biological organization / Carl Woese -- If the Tree of Life fell, would it make a sound? / W. Ford Doolittle -- Woe is the Tree of Life / William Martin -- The robustness of intermediary metabolism / Harold J. Morowitz, Daniel Broyles, and Howard Lasus -- Molecular sequences and the early history of life / Radhey Gupta -- Fulfilling Darwin's dream / James Lake ... [et al.] -- Paradigm lost / C.G. Kurland -- Contemporary issues in mitochondrial origins and evolution / Michael W. Gray -- On the origin and evolution of plastids / John M. Archibald and Patrick J. Keeling -- The karyomastigont model of eukaryosis / Hanna Melnitsky, Frederick A. Rainey and Lynn Margulis -- The missing piece: the microtubule cytoskeleton and the origin of eukaryotes / Michael F. Dolan -- Heritable microorganisms and reproductive parasitism / John H. Werren