S Wikipedije, slobodne enciklopedije
Eksportni protein fosforiliziranog adaptera RNK jest protein koji je kod ljudi kodiran genom PHAX sa hromosoma 5 .[ 5] [ 6]
Dužina polipeptidnog lanca je 394 aminokiseline , а molekulska težina 44.403 Da .[ 7]
10 20 30 40 50 MALEVGDMED GQLSDSDSDM TVAPSDRPLQ LPKVLGGDSA MRAFQNTATA CAPVSHYRAV ESVDSSEESF SDSDDDSCLW KRKRQKCFNP PPKPEPFQFG QSSQKPPVAG GKKINNIWGA VLQEQNQDAV ATELGILGME GTIDRSRQSE TYNYLLAKKL RKESQEHTKD LDKELDEYMH GGKKMGSKEE ENGQGHLKRK RPVKDRLGNR PEMNYKGRYE ITAEDSQEKV ADEISFRLQE PKKDLIARVV RIIGNKKAIE LLMETAEVEQ NGGLFIMNGS RRRTPGGVFL NLLKNTPSIS EEQIKDIFYI ENQKEYENKK AARKRRTQVL GKKMKQAIKS LNFQEDDDTS RETFASDTNE ALASLDESQE GHAEAKLEAE EAIEVDHSHD LDIF
^ a b c GRCh38: Ensembl release 89: ENSG00000164902 - Ensembl , maj 2017^ a b c GRCm38: Ensembl release 89: ENSMUSG00000008301 - Ensembl , maj 2017^ "Human PubMed Reference:" . National Center for Biotechnology Information, U.S. National Library of Medicine .^ "Mouse PubMed Reference:" . National Center for Biotechnology Information, U.S. National Library of Medicine .^ Ohno M, Segref A, Bachi A, Wilm M, Mattaj IW (maj 2000). "PHAX, a mediator of U snRNA nuclear export whose activity is regulated by phosphorylation" . Cell . 101 (2): 187–98. doi :10.1016/S0092-8674(00)80829-6 PMID 10786834 . S2CID 8938256 . ^ "Entrez Gene: RNUXA RNA U, small nuclear RNA export adaptor (phosphorylation regulated)" .^ "UniProt, Q9H814" (jezik: engleski). Pristupljeno 18. 10. 2021 .
Maruyama K, Sugano S (1994). "Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides". Gene . 138 (1–2): 171–4. doi :10.1016/0378-1119(94)90802-8 . PMID 8125298 . Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, et al. (1997). "Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library". Gene . 200 (1–2): 149–56. doi :10.1016/S0378-1119(97)00411-3 . PMID 9373149 . Segref A, Mattaj IW, Ohno M (2001). "The evolutionarily conserved region of the U snRNA export mediator PHAX is a novel RNA-binding domain that is essential for U snRNA export" . RNA . 7 (3): 351–60. doi :10.1017/S1355838201002278 . PMC 1370092 PMID 11333016 . Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences" . Proc. Natl. Acad. Sci. U.S.A . 99 (26): 16899–903. doi :10.1073/pnas.242603899 PMC 139241 PMID 12477932 . Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs" . Nat. Genet . 36 (1): 40–5. doi :10.1038/ng1285 PMID 14702039 . Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)" . Genome Res . 14 (10B): 2121–7. doi :10.1101/gr.2596504 . PMC 528928 PMID 15489334 . Boulon S, Verheggen C, Jady BE, et al. (2005). "PHAX and CRM1 are required sequentially to transport U3 snoRNA to nucleoli" . Mol. Cell . 16 (5): 777–87. doi :10.1016/j.molcel.2004.11.013 PMID 15574332 . Watkins NJ, Lemm I, Ingelfinger D, et al. (2005). "Assembly and maturation of the U3 snoRNP in the nucleoplasm in a large dynamic multiprotein complex". Mol. Cell . 16 (5): 789–98. doi :10.1016/j.molcel.2004.11.012 . hdl :11858/00-001M-0000-0012-EB89-8 PMID 15574333 . 
