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Study on antibacterial mechanism of copper-bearing austenitic antibacterial stainless steel by atomic force microscopy

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Abstract

A study was made on the antibacterial mechanism of copper-bearing austenitic antibacterial stainless steel by a series of methods such as atomic force microscopy (AFM) observation, force–distance curves and inductively coupled plasma mass spectrometer test. It was observed by AFM that the structure of the outer cell membrane responsible for the cell permeability was substantially changed for the bacteria after contacting with the antibacterial stainless steel, showing that cell walls were seriously damaged and a lot of contents in the cells leaked. It was also found that the adhesion force of bacteria to antibacterial stainless steel was considerably greater than that to the contrast steel, indicating that the electrostatic forces by Cu2+ being an important factor for killing bacteria.

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Acknowledgement

This work was financially supported by a fund from National Natural Science Foundation (No. 50671101).

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Authors and Affiliations

  1. Institute of Metal Research, Chinese Academy of Sciences, Shenyang, 110016, China

    Li Nan, Yongqian Liu, Manqi Lü & Ke Yang

  2. Graduate School of Chinese Academy of Sciences, Beijing, 100049, China

    Li Nan & Yongqian Liu

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  1. Li Nan
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Correspondence to Ke Yang.

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Nan, L., Liu, Y., Lü, M. et al. Study on antibacterial mechanism of copper-bearing austenitic antibacterial stainless steel by atomic force microscopy. J Mater Sci: Mater Med 19, 3057–3062 (2008). https://doi.org/10.1007/s10856-008-3444-z

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