The proteins that can cause CJD have a vital role in the nervous system.
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References
Bremer, J. et al. Nature Neurosci. doi:10.1038/nn.2483 (2010).
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Abbott, A. Healthy prions protect nerves. Nature (2010). https://doi.org/10.1038/news.2010.29
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DOI: https://doi.org/10.1038/news.2010.29