doi: 10.1126/science.287.5451.303.
Engineering the provitamin A (beta-carotene) biosynthetic pathway into (carotenoid-free) rice endosperm
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- PMID: 10634784
- DOI: 10.1126/science.287.5451.303
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Engineering the provitamin A (beta-carotene) biosynthetic pathway into (carotenoid-free) rice endosperm
Science.
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Abstract
Rice (Oryza sativa), a major staple food, is usually milled to remove the oil-rich aleurone layer that turns rancid upon storage, especially in tropical areas. The remaining edible part of rice grains, the endosperm, lacks several essential nutrients, such as provitamin A. Thus, predominant rice consumption promotes vitamin A deficiency, a serious public health problem in at least 26 countries, including highly populated areas of Asia, Africa, and Latin America. Recombinant DNA technology was used to improve its nutritional value in this respect. A combination of transgenes enabled biosynthesis of provitamin A in the endosperm.
Comment in
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Perspectives: plant biology. The green revolution strikes gold.Science. 2000 Jan 14;287(5451):241-3. doi: 10.1126/science.287.5451.241. Science. 2000. PMID: 10660423 No abstract available.
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To improve nutrition for the world's population.Science. 2000 Jun 16;288(5473):1966-7. doi: 10.1126/science.288.5473.1966. Science. 2000. PMID: 10877713 No abstract available.
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