This site needs JavaScript to work properly. Please enable it to take advantage of the complete set of features!

Skip to main page content

Email citation

Add to Collections

Your saved search

Name of saved search:

Search terms:

Test search terms

Would you like email updates of new search results?

Yes
No

Email: (change)

Frequency:

Which day?

Which day?

Report format:

Send at most:

Send even when there aren't any new results

Optional text in email:

Your RSS Feed

. 2012 Jun 15;336(6087):1386-7.

doi: 10.1126/science.1224398.

Physiology. COX-2 inhibitors and cardiovascular risk

Christopher P Cannon¹, Paul J Cannon

Affiliations

Affiliation

¹ Thrombolysis in Myocardial Infarction Study Group, Cardiovascular Division, Brigham and Women's Hospital, Harvard Medical School, 75 Francis Street, Boston, MA 02115, USA. cpcannon@partners.org

PMID: 22700906
DOI: 10.1126/science.1224398

Physiology. COX-2 inhibitors and cardiovascular risk

Christopher P Cannon et al. Science. 2012.

. 2012 Jun 15;336(6087):1386-7.

doi: 10.1126/science.1224398.

Authors

Christopher P Cannon¹, Paul J Cannon

Affiliation

¹ Thrombolysis in Myocardial Infarction Study Group, Cardiovascular Division, Brigham and Women's Hospital, Harvard Medical School, 75 Francis Street, Boston, MA 02115, USA. cpcannon@partners.org

PMID: 22700906
DOI: 10.1126/science.1224398

No abstract available

PubMed Disclaimer

Similar articles

COX-2 inhibitors and cardiovascular risk.
Funk CD, FitzGerald GA. Funk CD, et al. J Cardiovasc Pharmacol. 2007 Nov;50(5):470-9. doi: 10.1097/FJC.0b013e318157f72d. J Cardiovasc Pharmacol. 2007. PMID: 18030055 Review.
Marked interindividual variability in the response to selective inhibitors of cyclooxygenase-2.
Fries S, Grosser T, Price TS, Lawson JA, Kapoor S, DeMarco S, Pletcher MT, Wiltshire T, FitzGerald GA. Fries S, et al. Gastroenterology. 2006 Jan;130(1):55-64. doi: 10.1053/j.gastro.2005.10.002. Gastroenterology. 2006. PMID: 16401468 Clinical Trial.
[Innovation of anti-inflammatory drugs--inhibition of cyclooxygenases].
Guo ZR. Guo ZR. Yao Xue Xue Bao. 2005 Nov;40(11):967-9. Yao Xue Xue Bao. 2005. PMID: 16499077 Review. Chinese. No abstract available.
The pharmacology of selective inhibition of COX-2.
Grosser T. Grosser T. Thromb Haemost. 2006 Oct;96(4):393-400. Thromb Haemost. 2006. PMID: 17003913 Review.
Stronger inhibition by nonsteroid anti-inflammatory drugs of cyclooxygenase-1 in endothelial cells than platelets offers an explanation for increased risk of thrombotic events.
Mitchell JA, Lucas R, Vojnovic I, Hasan K, Pepper JR, Warner TD. Mitchell JA, et al. FASEB J. 2006 Dec;20(14):2468-75. doi: 10.1096/fj.06-6615com. FASEB J. 2006. PMID: 17142796

See all similar articles

Cited by

High Levels of Thromboxane (TX) Are Associated with the Sex-Dependent Non-Dipping Phenomenon in Ischemic Stroke Patients.
Drozd A, Szczuko M, Bohatyrewicz A, Jurewicz A, Kotlęga D. Drozd A, et al. J Clin Med. 2022 May 9;11(9):2652. doi: 10.3390/jcm11092652. J Clin Med. 2022. PMID: 35566778 Free PMC article.
Non-steroidal anti-inflammatory drugs attenuate the vascular responses in aging metabolic syndrome rats.
Rubio-Ruiz ME, Pérez-Torres I, Diaz-Diaz E, Pavón N, Guarner-Lans V. Rubio-Ruiz ME, et al. Acta Pharmacol Sin. 2014 Nov;35(11):1364-74. doi: 10.1038/aps.2014.67. Epub 2014 Sep 29. Acta Pharmacol Sin. 2014. PMID: 25263337 Free PMC article.
A genomic exploration identifies mechanisms that may explain adverse cardiovascular effects of COX-2 inhibitors.
Brænne I, Willenborg C, Tragante V, Kessler T, Zeng L, Reiz B, Kleinecke M, von Ameln S, Willer CJ, Laakso M, Wild PS, Zeller T, Wallentin L, Franks PW, Salomaa V, Dehghan A, Meitinger T, Samani NJ, Asselbergs FW, Erdmann J, Schunkert H. Brænne I, et al. Sci Rep. 2017 Aug 31;7(1):10252. doi: 10.1038/s41598-017-10928-4. Sci Rep. 2017. PMID: 28860667 Free PMC article.
Anti-Inflammatory Drugs Remodel the Tumor Immune Environment to Enhance Immune Checkpoint Blockade Efficacy.
Pelly VS, Moeini A, Roelofsen LM, Bonavita E, Bell CR, Hutton C, Blanco-Gomez A, Banyard A, Bromley CP, Flanagan E, Chiang SC, Jørgensen C, Schumacher TN, Thommen DS, Zelenay S. Pelly VS, et al. Cancer Discov. 2021 Oct;11(10):2602-2619. doi: 10.1158/2159-8290.CD-20-1815. Epub 2021 May 24. Cancer Discov. 2021. PMID: 34031121 Free PMC article.
Aminothiazoles inhibit osteoclastogenesis and PGE₂ production in LPS-stimulated co-cultures of periodontal ligament and RAW 264.7 cells, and RANKL-mediated osteoclastogenesis and bone resorption in PBMCs.
Kats A, Gerasimcik N, Näreoja T, Nederberg J, Grenlöv S, Lagnöhed E, Desai S, Andersson G, Yucel-Lindberg T. Kats A, et al. J Cell Mol Med. 2019 Feb;23(2):1152-1163. doi: 10.1111/jcmm.14015. Epub 2018 Dec 1. J Cell Mol Med. 2019. PMID: 30506812 Free PMC article.

See all "Cited by" articles

MeSH terms

Actions
Actions
Actions
Actions
Actions
Actions
Actions
Actions
Actions
Actions
Actions
Actions
Actions
Actions
Actions

Substances

Actions
Actions
Actions

LinkOut - more resources

Full Text Sources
- Atypon
- Ovid Technologies, Inc.
Medical
- MedlinePlus Health Information
Research Materials
- NCI CPTC Antibody Characterization Program