Good mass spectrometry and its place in good science
- PMID: 22707172
- DOI: 10.1002/jms.3038
Good mass spectrometry and its place in good science
Erratum in
- J Mass Spectrom. 2012 Dec;47(12):1671
Abstract
The mass spectrometry community has expanded as instruments became more powerful, user-friendly, affordable and readily available. This opens up opportunities for novice users to perform high impact research, using highly advanced instrumentation. This introductory tutorial is targeted at the novice user working in a research setting. It aims to offer the benefit of other people's experiences and to help newcomers avoid known pitfalls and problematic issues. It discusses some of the essential features of sound analytical chemistry and highlights the need to use validated analytical methods that provide high quality results along with a measure of their uncertainty. Examples are used to illustrate potential pitfalls and their consequences.
Copyright © 2012 John Wiley & Sons, Ltd.
Similar articles
-
Mass spectrometry-based targeted quantitative proteomics: achieving sensitive and reproducible detection of proteins.Proteomics. 2012 Apr;12(8):1093-110. doi: 10.1002/pmic.201100387. Proteomics. 2012. PMID: 22577011 Review.
-
Guidelines for experimental design and data analysis of proteomic mass spectrometry-based experiments.Amino Acids. 2011 Feb;40(2):259-60. doi: 10.1007/s00726-010-0750-9. Epub 2010 Oct 1. Amino Acids. 2011. PMID: 20886359 No abstract available.
-
Guidelines for reporting the use of mass spectrometry in proteomics.Nat Biotechnol. 2008 Aug;26(8):860-1. doi: 10.1038/nbt0808-860. Nat Biotechnol. 2008. PMID: 18688232 No abstract available.
-
Guidelines for reporting the use of mass spectrometry informatics in proteomics.Nat Biotechnol. 2008 Aug;26(8):862. doi: 10.1038/nbt0808-862. Nat Biotechnol. 2008. PMID: 18688233 No abstract available.
-
Parallel Reaction Monitoring: A Targeted Experiment Performed Using High Resolution and High Mass Accuracy Mass Spectrometry.Int J Mol Sci. 2015 Dec 2;16(12):28566-81. doi: 10.3390/ijms161226120. Int J Mol Sci. 2015. PMID: 26633379 Free PMC article. Review.
Cited by
-
Special Issue "Protein Analysis by Mass Spectrometry".Molecules. 2023 Mar 10;28(6):2541. doi: 10.3390/molecules28062541. Molecules. 2023. PMID: 36985512 Free PMC article.
-
Mass Spectrometry-Based Evaluation of the Bland-Altman Approach: Review, Discussion, and Proposal.Molecules. 2023 Jun 21;28(13):4905. doi: 10.3390/molecules28134905. Molecules. 2023. PMID: 37446566 Free PMC article. Review.
-
Observations from the Proteomics Bench.Proteomes. 2024 Feb 6;12(1):6. doi: 10.3390/proteomes12010006. Proteomes. 2024. PMID: 38390966 Free PMC article.
-
Optimization of HS-SPME for GC-MS Analysis and Its Application in Characterization of Volatile Compounds in Sweet Potato.Molecules. 2021 Sep 25;26(19):5808. doi: 10.3390/molecules26195808. Molecules. 2021. PMID: 34641353 Free PMC article.
-
A Single Laboratory Validation for the Analysis of Underivatized β-N-Methylamino-L-Alanine (BMAA).Neurotox Res. 2021 Feb;39(1):49-71. doi: 10.1007/s12640-019-00137-4. Epub 2019 Dec 11. Neurotox Res. 2021. PMID: 31823228
Publication types
MeSH terms
LinkOut - more resources
Full Text Sources
