Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Comment
. 2014 Jan;10(1):e1004093.
doi: 10.1371/journal.pgen.1004093. Epub 2014 Jan 16.

How much is that in dog years? The advent of canine population genomics

Affiliations
Comment

How much is that in dog years? The advent of canine population genomics

Greger Larson et al. PLoS Genet. 2014 Jan.
No abstract available

PubMed Disclaimer

Conflict of interest statement

The authors have declared that no competing interests exist.

Figures

Figure 1
Figure 1. Summary of the demographic model and sampling from Freedman et al. .
Their critical inclusion of data from the Australian Dingo illustrates that high copy number in AMY2B is not a basal trait in dogs. The reciprocal monophyly of wild and domestic suggests that, despite the geographical diversity of sampling, descendants of the wolf population that contributed to dog domestication are not represented and may only be accessible using ancient DNA.

Comment on

  • Genome sequencing highlights the dynamic early history of dogs.
    Freedman AH, Gronau I, Schweizer RM, Ortega-Del Vecchyo D, Han E, Silva PM, Galaverni M, Fan Z, Marx P, Lorente-Galdos B, Beale H, Ramirez O, Hormozdiari F, Alkan C, Vilà C, Squire K, Geffen E, Kusak J, Boyko AR, Parker HG, Lee C, Tadigotla V, Wilton A, Siepel A, Bustamante CD, Harkins TT, Nelson SF, Ostrander EA, Marques-Bonet T, Wayne RK, Novembre J. Freedman AH, et al. PLoS Genet. 2014 Jan;10(1):e1004016. doi: 10.1371/journal.pgen.1004016. Epub 2014 Jan 16. PLoS Genet. 2014. PMID: 24453982 Free PMC article.

Similar articles

Cited by

References

    1. Freedman AH, Gronau I, Schweizer RM, Ortega-Del Vecchyo D, Han E, et al. (2014) Genome sequencing highlights the dynamic early history of dogs. PLoS Genet 10: e1004016 doi:10.1371/journal.pgen.1004016 - DOI - PMC - PubMed
    1. Wang G-D, Zhai WW, Yang H-C, Fan R-X, Cao X, et al. (2013) The genomics of selection in dogs and the parallel evolution between dogs and humans. Nature Commun 4: 1860 doi:10.1038/ncomms2814 - DOI - PubMed
    1. Vilà C, Savolainen P, Maldonado JE, Amorim IR, Rice JE, et al. (1997) Multiple and ancient origins of the domestic dog. Science 276: 1687–1689. - PubMed
    1. Savolainen P, Zhang YP, Luo J, Lundeberg J, Leitner T (2002) Genetic evidence for an East Asian origin of domestic dogs. Science 298: 1610–1613. - PubMed
    1. Axelsson E, Ratnakumar A, Arendt M-J, Maqbool K, Webster MT, et al. (2013) The genomic signature of dog domestication reveals adaptation to a starch-rich diet. Nature 495: 360–364. - PubMed

Grants and funding

The authors received no specific funding for this article.