Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2023 Aug 31:12:211.
doi: 10.4103/abr.abr_166_22. eCollection 2023.

The Effect of Laparoscopic Sleeve Gastrectomy on Serum Levels of Vitamin A, D and B12 and Iron Profile on Patients with Morbid Obesity

Fariborz Rashnoo  1 , Arsham Seifinezhad  2 , Hamidreza Zefreh  2 , Erfan Sheikhbahaei  2   3 , Amir Hossein Irajpour  1
Affiliations

The Effect of Laparoscopic Sleeve Gastrectomy on Serum Levels of Vitamin A, D and B12 and Iron Profile on Patients with Morbid Obesity

Fariborz Rashnoo et al. Adv Biomed Res. .

Abstract

Background: One of the concerns after bariatric surgery is the lack of nutrients and vitamins due to anatomical and physiological changes that occur after the surgery. The aim of the present study is to evaluate the effect of laparoscopic sleeve gastrectomy on these nutrients and vitamins.

Materials and methods: This prospective study was performed in Tehran and all the patients who met the inclusion criteria before the surgery were tested for serum levels of vitamins A, B12, D, ferritin, serum iron, and TIBC. The patients were tested once again for the same micronutrients, one year after surgery.

Results: A total of 120 patients had the inclusion criteria and all of them completed the follow-up period. Of the patients, 64.2% (77 patients) were female and 35.8% (43 patients) were male. The mean weight of the patients was 122.1 ± 14.8 kg and the mean BMI of patients before surgery was 43.6 ± 4.4 kg/m2. Comparing these parameters before and after surgery showed that serum levels of vitamins A and B12, ferritin, and TIBC were not significantly different from before surgery. However, vitamin D levels after surgery were significantly higher than before (p < 0.001).

Conclusion: The result of the present study demonstrated that laparoscopic sleeve gastrectomy is one of the most effective surgical methods for obesity treatment and does not cause a lack of nutrients and vitamins in long term and does not require supplementation. In addition, it promotes serum levels of vitamin D, which is effective in preventing the effects of vitamin D deficiency in obese patients.

Keywords: Bariatric surgery; nutrients; obesity; vitamins.

PubMed Disclaimer

Conflict of interest statement

There are no conflicts of interest.

Figures

Figure 1
Figure 1
Comparison of classified body mass index before and after surgery
See this image and copyright information in PMC

Similar articles

See all similar articles

Cited by

  • Bariatric Surgery and Metabolic Status.
    Różańska-Walędziak A, Wyszomirski K, Kaszuba M, Mierzejewska A, Skopińska E, Walędziak M. Różańska-Walędziak A, et al. Medicina (Kaunas). 2024 Sep 20;60(9):1532. doi: 10.3390/medicina60091532. Medicina (Kaunas). 2024. PMID: 39336575 Free PMC article.

References

    1. Gill TP, Antipatis VJ, James WP. The global epidemic of obesity. Asia Pac J ClinNutr. 1999;8:75–81. - PubMed
    1. Trends in adult body-mass index in 200 countries from 1975 to 2014: A pooled analysis of 1698 population-based measurement studies with 19·2 million participants. Lancet. 2016;387:1377–96. - PMC - PubMed
    1. Kontis V, Mathers CD, Rehm J, Stevens GA, Shield KD, Bonita R, et al. Contribution of six risk factors to achieving the 25×25 non-communicable disease mortality reduction target: Amodelling study. Lancet. 2014;384:427–37. - PubMed
    1. Melissas J, Christodoulakis M, Schoretsanitis G, Sanidas E, Ganotakis E, Michaloudis D, et al. Obesity-associated disorders before and after weight reduction by vertical banded gastroplasty in morbidly vs super obese individuals. ObesSurg. 2001;11:475–81. - PubMed
    1. Melissas J, Christodoulakis M, Spyridakis M, Schoretsanitis G, Michaloudis D, Papavasiliou E, et al. Disorders associated with clinically severe obesity: Significant improvement after surgical weight reduction. South Med J. 1998;91:1143–8. - PubMed

LinkOut - more resources