I suspect that I somehow have the wrong combination of some tooling in order to regenerate configure, but the regenerated files check seems to be failing due to runstatedir being removed. Following https://devguide.python.org/setup/#regenerate-configure, I did install all the requisite packages from Homebrew and am specifically using autoconf 2.69.

Regenerating configure isn't so simple anymore :( See https://bugs.python.org/issue44035 where @tiran provides a link to containers that provide the canonical version of autoconf.

Ugh, so now we require either Linux or some container runtime in order to update ./configure? It might be time to update to either autoconf 2.71 or consider moving to CMake.

I'm downloading Docker Desktop for Mac now, so hopefully I can get this PR fixed in the next week or so.

@brettcannon this indeed addresses one of the issues I had with the WebAssembly build on Mac with https://github.com/ethanhs/python-wasm