KEGG   Homo sapiens (human): 9184
Entry
9184              CDS       T01001                                 
Symbol
BUB3, BUB3L, hBUB3
Name
(RefSeq) BUB3 mitotic checkpoint protein
  KO
K02180  cell cycle arrest protein BUB3
Organism
hsa  Homo sapiens (human)
Pathway
hsa04110  Cell cycle
hsa05166  Human T-cell leukemia virus 1 infection
Network
nt06160  Human T-cell leukemia virus 1 (HTLV-1)
nt06230  Cell cycle (cancer)
nt06515  Regulation of kinetochore-microtubule interactions
  Element
N00493  Spindle assembly checkpoint signaling
N01529  Recruitment and formation of the MCC
N01533  Disassembly of MCC
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09160 Human Diseases
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    9184 (BUB3)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03041 Spliceosome [BR:hsa03041]
    9184 (BUB3)
   03036 Chromosome and associated proteins [BR:hsa03036]
    9184 (BUB3)
Spliceosome [BR:hsa03041]
 Complex A
  Other components
   Complex A specific factors
    9184 (BUB3)
Chromosome and associated proteins [BR:hsa03036]
 Eukaryotic type
  Centromeric chromatin formation proteins
   SAC (spindle assembly checkpoint) factors
    Core SAC proteins
     9184 (BUB3)
SSDB
Motif
Pfam: WD40 WD40_Prp19 WD40_CDC20-Fz Beta-prop_EML_2 WD40_WDHD1_1st WDR55 Beta-prop_TEP1_C Beta-prop_TEP1_2nd Beta-prop_RIG_2nd Beta-prop_WDR90_POC16_2nd EIF3I Beta-prop_WDR75_1st Beta-prop_EML Beta-prop_IFT140_1st Beta-prop_SPT8 WD40_MABP1-WDR62_2nd WD40_RFWD3 Beta-prop_EIPR1 Beta-prop_RSE1_2nd WDR90_beta-prop_4th Beta-prop_CAF1B_HIR1 WD40_MABP1-WDR62_1st Beta-prop_Vps41 Beta-prop_DCAF12 NBCH_WD40 PQQ_3
Other DBs
NCBI-GeneID: 9184
NCBI-ProteinID: NP_004716
OMIM: 603719
HGNC: 1151
Ensembl: ENSG00000154473
UniProt: O43684
Position
10:123154402..123170467
AA seq 328 aa
MTGSNEFKLNQPPEDGISSVKFSPNTSQFLLVSSWDTSVRLYDVPANSMRLKYQHTGAVL
DCAFYDPTHAWSGGLDHQLKMHDLNTDQENLVGTHDAPIRCVEYCPEVNVMVTGSWDQTV
KLWDPRTPCNAGTFSQPEKVYTLSVSGDRLIVGTAGRRVLVWDLRNMGYVQQRRESSLKY
QTRCIRAFPNKQGYVLSSIEGRVAVEYLDPSPEVQKKKYAFKCHRLKENNIEQIYPVNAI
SFHNIHNTFATGGSDGFVNIWDPFNKKRLCQFHRYPTSIASLAFSNDGTTLAIASSYMYE
MDDTEHPEDGIFIRQVTDAETKPKSPCT
NT seq 987 nt   +upstreamnt  +downstreamnt
atgaccggttctaacgagttcaagctgaaccagccacccgaggatggcatctcctccgtg
aagttcagccccaacacctcccagttcctgcttgtctcctcctgggacacgtccgtgcgt
ctctacgatgtgccggccaactccatgcggctcaagtaccagcacaccggcgccgtcctg
gactgcgccttctacgatccaacgcatgcctggagtggaggactagatcatcaattgaaa
atgcatgatttgaacactgatcaagaaaatcttgttgggacccatgatgcccctatcaga
tgtgttgaatactgtccagaagtgaatgtgatggtcactggaagttgggatcagacagtt
aaactgtgggatcccagaactccttgtaatgctgggaccttctctcagcctgaaaaggta
tataccctctcagtgtctggagaccggctgattgtgggaacagcaggccgcagagtgttg
gtgtgggacttacggaacatgggttacgtgcagcagcgcagggagtccagcctgaaatac
cagactcgctgcatacgagcgtttccaaacaagcagggttatgtattaagctctattgaa
ggccgagtggcagttgagtatttggacccaagccctgaggtacagaagaagaagtatgcc
ttcaaatgtcacagactaaaagaaaataatattgagcagatttacccagtcaatgccatt
tcttttcacaatatccacaatacatttgccacaggtggttctgatggctttgtaaatatt
tgggatccatttaacaaaaagcgactgtgccaattccatcggtaccccacgagcatcgca
tcacttgccttcagtaatgatgggactacgcttgcaatagcgtcatcatatatgtatgaa
atggatgacacagaacatcctgaagatggtatcttcattcgccaagtgacagatgcagaa
acaaaacccaagtcaccatgtacttga

  All links  
Disease (1)   
   OMIM (1)   
Gene (22)   
   RefGene (3)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (14)   
   OC (1)   
Protein sequence (4)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (2)   
DNA sequence (32)   
   RefSeq(nuc) (2)   
   GenBank (15)   
   EMBL (15)   
Protein domain (26)   
   Pfam (26)   
All databases (85)   

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