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. 2004 Apr 14;16(Suppl):S61–S71. doi: 10.1105/tpc.016667

Sex-determining mechanisms in land plants.

Milos Tanurdzic 1, Jo Ann Banks 1
PMCID: PMC2643385  PMID: 15084718

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Selected References

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  1. Ainsworth C., Crossley S., Buchanan-Wollaston V., Thangavelu M., Parker J. Male and female flowers of the dioecious plant sorrel show different patterns of MADS box gene expression. Plant Cell. 1995 Oct;7(10):1583–1598. doi: 10.1105/tpc.7.10.1583. [DOI] [PMC free article] [PubMed] [Google Scholar]
  2. Atanassov I., Delichère C., Filatov D. A., Charlesworth D., Negrutiu I., Monéger F. Analysis and evolution of two functional Y-linked loci in a plant sex chromosome system. Mol Biol Evol. 2001 Dec;18(12):2162–2168. doi: 10.1093/oxfordjournals.molbev.a003762. [DOI] [PubMed] [Google Scholar]
  3. Baker B. S., Ridge K. A. Sex and the single cell. I. On the action of major loci affecting sex determination in Drosophila melanogaster. Genetics. 1980 Feb;94(2):383–423. doi: 10.1093/genetics/94.2.383. [DOI] [PMC free article] [PubMed] [Google Scholar]
  4. Barrett Spencer C. H. The evolution of plant sexual diversity. Nat Rev Genet. 2002 Apr;3(4):274–284. doi: 10.1038/nrg776. [DOI] [PubMed] [Google Scholar]
  5. Bensen R. J., Johal G. S., Crane V. C., Tossberg J. T., Schnable P. S., Meeley R. B., Briggs S. P. Cloning and characterization of the maize An1 gene. Plant Cell. 1995 Jan;7(1):75–84. doi: 10.1105/tpc.7.1.75. [DOI] [PMC free article] [PubMed] [Google Scholar]
  6. Calderon-Urrea A., Dellaporta S. L. Cell death and cell protection genes determine the fate of pistils in maize. Development. 1999 Feb;126(3):435–441. doi: 10.1242/dev.126.3.435. [DOI] [PubMed] [Google Scholar]
  7. Charlesworth B. The evolution of chromosomal sex determination and dosage compensation. Curr Biol. 1996 Feb 1;6(2):149–162. doi: 10.1016/s0960-9822(02)00448-7. [DOI] [PubMed] [Google Scholar]
  8. Charlesworth Deborah. Plant sex determination and sex chromosomes. Heredity (Edinb) 2002 Feb;88(2):94–101. doi: 10.1038/sj.hdy.6800016. [DOI] [PubMed] [Google Scholar]
  9. Cline T. W. The interaction between daughterless and sex-lethal in triploids: a lethal sex-transforming maternal effect linking sex determination and dosage compensation in Drosophila melanogaster. Dev Biol. 1983 Feb;95(2):260–274. doi: 10.1016/0012-1606(83)90027-1. [DOI] [PubMed] [Google Scholar]
  10. DeLong A., Calderon-Urrea A., Dellaporta S. L. Sex determination gene TASSELSEED2 of maize encodes a short-chain alcohol dehydrogenase required for stage-specific floral organ abortion. Cell. 1993 Aug 27;74(4):757–768. doi: 10.1016/0092-8674(93)90522-r. [DOI] [PubMed] [Google Scholar]
  11. Delichère C., Veuskens J., Hernould M., Barbacar N., Mouras A., Negrutiu I., Monéger F. SlY1, the first active gene cloned from a plant Y chromosome, encodes a WD-repeat protein. EMBO J. 1999 Aug 2;18(15):4169–4179. doi: 10.1093/emboj/18.15.4169. [DOI] [PMC free article] [PubMed] [Google Scholar]
  12. Dellaporta S. L., Calderon-Urrea A. The sex determination process in maize. Science. 1994 Dec 2;266(5190):1501–1505. doi: 10.1126/science.7985019. [DOI] [PubMed] [Google Scholar]
  13. Deputy J. C., Ming R., Ma H., Liu Z., Fitch M. M. M., Wang M., Manshardt R., Stiles J. I. Molecular markers for sex determination in papaya ( Carica papaya L.). Theor Appl Genet. 2002 Jul 12;106(1):107–111. doi: 10.1007/s00122-002-0995-0. [DOI] [PubMed] [Google Scholar]
  14. Desfeux C., Maurice S., Henry J. P., Lejeune B., Gouyon P. H. Evolution of reproductive systems in the genus Silene. Proc Biol Sci. 1996 Apr 22;263(1369):409–414. doi: 10.1098/rspb.1996.0062. [DOI] [PubMed] [Google Scholar]
  15. Elo Annakaisa, Lemmetyinen Juha, Turunen Marja-Leena, Tikka Liisa, Sopanen Tuomas. Three MADS-box genes similar to APETALA1 and FRUITFULL from silver birch (Betula pendula). Physiol Plant. 2001 May;112(1):95–103. doi: 10.1034/j.1399-3054.2001.1120113.x. [DOI] [PubMed] [Google Scholar]
  16. Farbos I., Veuskens J., Vyskot B., Oliveira M., Hinnisdaels S., Aghmir A., Mouras A., Negrutiu I. Sexual dimorphism in white campion: deletion on the Y chromosome results in a floral asexual phenotype. Genetics. 1999 Mar;151(3):1187–1196. doi: 10.1093/genetics/151.3.1187. [DOI] [PMC free article] [PubMed] [Google Scholar]
  17. Filatov D. A., Laporte V., Vitte C., Charlesworth D. DNA diversity in sex-linked and autosomal genes of the plant species Silene latifolia and Silene dioica. Mol Biol Evol. 2001 Aug;18(8):1442–1454. doi: 10.1093/oxfordjournals.molbev.a003930. [DOI] [PubMed] [Google Scholar]
  18. Filatov D. A., Monéger F., Negrutiu I., Charlesworth D. Low variability in a Y-linked plant gene and its implications for Y-chromosome evolution. Nature. 2000 Mar 23;404(6776):388–390. doi: 10.1038/35006057. [DOI] [PubMed] [Google Scholar]
  19. Filatov Dmitry A., Charlesworth Deborah. Substitution rates in the X- and Y-linked genes of the plants, Silene latifolia and S. dioica. Mol Biol Evol. 2002 Jun;19(6):898–907. doi: 10.1093/oxfordjournals.molbev.a004147. [DOI] [PubMed] [Google Scholar]
  20. Grabowska-Joachimiak Aleksandra, Joachimiak Andrzej. C-banded karyotypes of two Silene species with heteromorphic sex chromosomes. Genome. 2002 Apr;45(2):243–252. doi: 10.1139/g01-143. [DOI] [PubMed] [Google Scholar]
  21. Graves J. A., Schmidt M. M. Mammalian sex chromosomes: design or accident? Curr Opin Genet Dev. 1992 Dec;2(6):890–901. doi: 10.1016/s0959-437x(05)80112-1. [DOI] [PubMed] [Google Scholar]
  22. Guttman D. S., Charlesworth D. An X-linked gene with a degenerate Y-linked homologue in a dioecious plant. Nature. 1998 May 21;393(6682):263–266. doi: 10.1038/30492. [DOI] [PubMed] [Google Scholar]
  23. Hardenack S., Ye D., Saedler H., Grant S. Comparison of MADS box gene expression in developing male and female flowers of the dioecious plant white campion. Plant Cell. 1994 Dec;6(12):1775–1787. doi: 10.1105/tpc.6.12.1775. [DOI] [PMC free article] [PubMed] [Google Scholar]
  24. Hawley R. Scott. The human Y chromosome: rumors of its death have been greatly exaggerated. Cell. 2003 Jun 27;113(7):825–828. doi: 10.1016/s0092-8674(03)00470-7. [DOI] [PubMed] [Google Scholar]
  25. Heuer S., Hansen S., Bantin J., Brettschneider R., Kranz E., Lörz H., Dresselhaus T. The maize MADS box gene ZmMADS3 affects node number and spikelet development and is co-expressed with ZmMADS1 during flower development, in egg cells, and early embryogenesis. Plant Physiol. 2001 Sep;127(1):33–45. doi: 10.1104/pp.127.1.33. [DOI] [PMC free article] [PubMed] [Google Scholar]
  26. Hodgkin J. Sex determination and dosage compensation in Caenorhabditis elegans. Annu Rev Genet. 1987;21:133–154. doi: 10.1146/annurev.ge.21.120187.001025. [DOI] [PubMed] [Google Scholar]
  27. Ishizaki Kimitsune, Shimizu-Ueda Yuu, Okada Sachiko, Yamamoto Masayuki, Fujisawa Masaki, Yamato Katsuyuki T., Fukuzawa Hideya, Ohyama Kanji. Multicopy genes uniquely amplified in the Y chromosome-specific repeats of the liverwort Marchantia polymorpha. Nucleic Acids Res. 2002 Nov 1;30(21):4675–4681. doi: 10.1093/nar/gkf604. [DOI] [PMC free article] [PubMed] [Google Scholar]
  28. Jegalian K., Page D. C. A proposed path by which genes common to mammalian X and Y chromosomes evolve to become X inactivated. Nature. 1998 Aug 20;394(6695):776–780. doi: 10.1038/29522. [DOI] [PubMed] [Google Scholar]
  29. Kamachi S., Sekimoto H., Kondo N., Sakai S. Cloning of a cDNA for a 1-aminocyclopropane-1-carboxylate synthase that is expressed during development of female flowers at the apices of Cucumis sativus L. Plant Cell Physiol. 1997 Nov;38(11):1197–1206. doi: 10.1093/oxfordjournals.pcp.a029106. [DOI] [PubMed] [Google Scholar]
  30. Kater M. M., Franken J., Carney K. J., Colombo L., Angenent G. C. Sex determination in the monoecious species cucumber is confined to specific floral whorls. Plant Cell. 2001 Mar;13(3):481–493. doi: 10.1105/tpc.13.3.481. [DOI] [PMC free article] [PubMed] [Google Scholar]
  31. Lahn B. T., Page D. C. Four evolutionary strata on the human X chromosome. Science. 1999 Oct 29;286(5441):964–967. doi: 10.1126/science.286.5441.964. [DOI] [PubMed] [Google Scholar]
  32. Lardon A., Georgiev S., Aghmir A., Le Merrer G., Negrutiu I. Sexual dimorphism in white campion: complex control of carpel number is revealed by y chromosome deletions. Genetics. 1999 Mar;151(3):1173–1185. doi: 10.1093/genetics/151.3.1173. [DOI] [PMC free article] [PubMed] [Google Scholar]
  33. Lebel-Hardenack Sabine, Hauser Elizabeth, Law Teresa F., Schmid Jurg, Grant Sarah R. Mapping of sex determination loci on the white campion (Silene latifolia) Y chromosome using amplified fragment length polymorphism. Genetics. 2002 Feb;160(2):717–725. doi: 10.1093/genetics/160.2.717. [DOI] [PMC free article] [PubMed] [Google Scholar]
  34. Matsunaga S., Kawano S., Takano H., Uchida H., Sakai A., Kuroiwa T. Isolation and developmental expression of male reproductive organ-specific genes in a dioecious campion, Melandrium album (Silene latifolia). Plant J. 1996 Oct;10(4):679–689. doi: 10.1046/j.1365-313x.1996.10040679.x. [DOI] [PubMed] [Google Scholar]
  35. Moore Richard C., Kozyreva Olga, Lebel-Hardenack Sabine, Siroky Jiri, Hobza Roman, Vyskot Boris, Grant Sarah R. Genetic and functional analysis of DD44, a sex-linked gene from the dioecious plant Silene latifolia, provides clues to early events in sex chromosome evolution. Genetics. 2003 Jan;163(1):321–334. doi: 10.1093/genetics/163.1.321. [DOI] [PMC free article] [PubMed] [Google Scholar]
  36. Negrutiu I., Vyskot B., Barbacar N., Georgiev S., Moneger F. Dioecious plants. A key to the early events of sex chromosome evolution. Plant Physiol. 2001 Dec;127(4):1418–1424. [PMC free article] [PubMed] [Google Scholar]
  37. Okada S., Fujisawa M., Sone T., Nakayama S., Nishiyama R., Takenaka M., Yamaoka S., Sakaida M., Kono K., Takahama M. Construction of male and female PAC genomic libraries suitable for identification of Y-chromosome-specific clones from the liverwort, Marchantia polymorpha. Plant J. 2000 Nov;24(3):421–428. doi: 10.1046/j.1365-313x.2000.00882.x. [DOI] [PubMed] [Google Scholar]
  38. Okada S., Sone T., Fujisawa M., Nakayama S., Takenaka M., Ishizaki K., Kono K., Shimizu-Ueda Y., Hanajiri T., Yamato K. T. The Y chromosome in the liverwort Marchantia polymorpha has accumulated unique repeat sequences harboring a male-specific gene. Proc Natl Acad Sci U S A. 2001 Jul 31;98(16):9454–9459. doi: 10.1073/pnas.171304798. [DOI] [PMC free article] [PubMed] [Google Scholar]
  39. Oliver Brian. Genetic control of germline sexual dimorphism in Drosophila. Int Rev Cytol. 2002;219:1–60. doi: 10.1016/s0074-7696(02)19010-3. [DOI] [PubMed] [Google Scholar]
  40. Olszewski Neil, Sun Tai-Ping, Gubler Frank. Gibberellin signaling: biosynthesis, catabolism, and response pathways. Plant Cell. 2002;14 (Suppl):S61–S80. doi: 10.1105/tpc.010476. [DOI] [PMC free article] [PubMed] [Google Scholar]
  41. Park J. H., Ishikawa Y., Yoshida R., Kanno A., Kameya T. Expression of AODEF, a B-functional MADS-box gene, in stamens and inner tepals of the dioecious species Asparagus officinalis L. Plant Mol Biol. 2003 Apr;51(6):867–875. doi: 10.1023/a:1023097202885. [DOI] [PubMed] [Google Scholar]
  42. Peng J., Richards D. E., Hartley N. M., Murphy G. P., Devos K. M., Flintham J. E., Beales J., Fish L. J., Worland A. J., Pelica F. 'Green revolution' genes encode mutant gibberellin response modulators. Nature. 1999 Jul 15;400(6741):256–261. doi: 10.1038/22307. [DOI] [PubMed] [Google Scholar]
  43. Pryer K. M., Schneider H., Smith A. R., Cranfill R., Wolf P. G., Hunt J. S., Sipes S. D. Horsetails and ferns are a monophyletic group and the closest living relatives to seed plants. Nature. 2001 Feb 1;409(6820):618–622. doi: 10.1038/35054555. [DOI] [PubMed] [Google Scholar]
  44. Richards Donald E., King Kathryn E., Ait-Ali Tahar, Harberd Nicholas P. HOW GIBBERELLIN REGULATES PLANT GROWTH AND DEVELOPMENT: A Molecular Genetic Analysis of Gibberellin Signaling. Annu Rev Plant Physiol Plant Mol Biol. 2001 Jun;52(NaN):67–88. doi: 10.1146/annurev.arplant.52.1.67. [DOI] [PubMed] [Google Scholar]
  45. Rood S. B., Pharis R. P. Changes of Endogenous Gibberellin-like Substances with Sex Reversal of the Apical Inflorescence of Corn. Plant Physiol. 1980 Nov;66(5):793–796. doi: 10.1104/pp.66.5.793. [DOI] [PMC free article] [PubMed] [Google Scholar]
  46. Rozen Steve, Skaletsky Helen, Marszalek Janet D., Minx Patrick J., Cordum Holland S., Waterston Robert H., Wilson Richard K., Page David C. Abundant gene conversion between arms of palindromes in human and ape Y chromosomes. Nature. 2003 Jun 19;423(6942):873–876. doi: 10.1038/nature01723. [DOI] [PubMed] [Google Scholar]
  47. Sheppard L. A., Brunner A. M., Krutovskii K. V., Rottmann W. H., Skinner J. S., Vollmer S. S., Strauss S. H. A DEFICIENS homolog from the dioecious tree black cottonwood is expressed in female and male floral meristems of the two-whorled, unisexual flowers. Plant Physiol. 2000 Oct;124(2):627–640. doi: 10.1104/pp.124.2.627. [DOI] [PMC free article] [PubMed] [Google Scholar]
  48. Skaletsky Helen, Kuroda-Kawaguchi Tomoko, Minx Patrick J., Cordum Holland S., Hillier LaDeana, Brown Laura G., Repping Sjoerd, Pyntikova Tatyana, Ali Johar, Bieri Tamberlyn. The male-specific region of the human Y chromosome is a mosaic of discrete sequence classes. Nature. 2003 Jun 19;423(6942):825–837. doi: 10.1038/nature01722. [DOI] [PubMed] [Google Scholar]
  49. Spray C. R., Kobayashi M., Suzuki Y., Phinney B. O., Gaskin P., MacMillan J. The dwarf-1 (dt) Mutant of Zea mays blocks three steps in the gibberellin-biosynthetic pathway. Proc Natl Acad Sci U S A. 1996 Sep 17;93(19):10515–10518. doi: 10.1073/pnas.93.19.10515. [DOI] [PMC free article] [PubMed] [Google Scholar]
  50. Stout Stephen C., Clark Gregory B., Archer-Evans Sarah, Roux Stanley J. Rapid and efficient suppression of gene expression in a single-cell model system, Ceratopteris richardii. Plant Physiol. 2003 Mar;131(3):1165–1168. doi: 10.1104/pp.016949. [DOI] [PMC free article] [PubMed] [Google Scholar]
  51. Strain E., Hass B., Banks J. A. Characterization of mutations that feminize gametophytes of the fern Ceratopteris. Genetics. 2001 Nov;159(3):1271–1281. doi: 10.1093/genetics/159.3.1271. [DOI] [PMC free article] [PubMed] [Google Scholar]
  52. Takenaka M., Yamaoka S., Hanajiri T., Shimizu-Ueda Y., Yamato K. T., Fukuzawa H., Ohyama K. Direct transformation and plant regeneration of the haploid liverwort Marchantia polymorpha L. Transgenic Res. 2000 Jun;9(3):179–185. doi: 10.1023/a:1008963410465. [DOI] [PubMed] [Google Scholar]
  53. Trebitsh T., Staub J. E., O'Neill S. D. Identification of a 1-aminocyclopropane-1-carboxylic acid synthase gene linked to the female (F) locus that enhances female sex expression in cucumber. Plant Physiol. 1997 Mar;113(3):987–995. doi: 10.1104/pp.113.3.987. [DOI] [PMC free article] [PubMed] [Google Scholar]
  54. Urasaki N., Tokumoto M., Tarora K., Ban Y., Kayano T., Tanaka H., Oku H., Chinen I., Terauchi R. A male and hermaphrodite specific RAPD marker for papaya ( Carica papayaL.). Theor Appl Genet. 2002 Feb;104(2-3):281–285. doi: 10.1007/s001220100693. [DOI] [PubMed] [Google Scholar]
  55. Villeneuve A. M., Meyer B. J. The regulatory hierarchy controlling sex determination and dosage compensation in Caenorhabditis elegans. Adv Genet. 1990;27:117–188. doi: 10.1016/s0065-2660(08)60025-5. [DOI] [PubMed] [Google Scholar]
  56. WESTERGAARD M. The mechanism of sex determination in dioecious flowering plants. Adv Genet. 1958;9:217–281. doi: 10.1016/s0065-2660(08)60163-7. [DOI] [PubMed] [Google Scholar]
  57. Winkler R. G., Helentjaris T. The maize Dwarf3 gene encodes a cytochrome P450-mediated early step in Gibberellin biosynthesis. Plant Cell. 1995 Aug;7(8):1307–1317. doi: 10.1105/tpc.7.8.1307. [DOI] [PMC free article] [PubMed] [Google Scholar]
  58. Wu H. M., Cheun A. Y. Programmed cell death in plant reproduction. Plant Mol Biol. 2000 Oct;44(3):267–281. doi: 10.1023/a:1026536324081. [DOI] [PubMed] [Google Scholar]
  59. Yamasaki S., Fujii N., Matsuura S., Mizusawa H., Takahashi H. The M locus and ethylene-controlled sex determination in andromonoecious cucumber plants. Plant Cell Physiol. 2001 Jun;42(6):608–619. doi: 10.1093/pcp/pce076. [DOI] [PubMed] [Google Scholar]
  60. Yu D., Kotilainen M., Pöllänen E., Mehto M., Elomaa P., Helariutta Y., Albert V. A., Teeri T. H. Organ identity genes and modified patterns of flower development in Gerbera hybrida (Asteraceae) Plant J. 1999 Jan;17(1):51–62. doi: 10.1046/j.1365-313x.1999.00351.x. [DOI] [PubMed] [Google Scholar]

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