Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 1999 May 27;399(6734):323-9.
doi: 10.1038/20601.

Evidence for lateral gene transfer between Archaea and bacteria from genome sequence of Thermotoga maritima

K E Nelson  1 , R A Clayton, S R Gill, M L Gwinn, R J Dodson, D H Haft, E K Hickey, J D Peterson, W C Nelson, K A Ketchum, L McDonald, T R Utterback, J A Malek, K D Linher, M M Garrett, A M Stewart, M D Cotton, M S Pratt, C A Phillips, D Richardson, J Heidelberg, G G Sutton, R D Fleischmann, J A Eisen, O White, S L Salzberg, H O Smith, J C Venter, C M Fraser
Affiliations

Evidence for lateral gene transfer between Archaea and bacteria from genome sequence of Thermotoga maritima

K E Nelson et al. Nature. .

Abstract

The 1,860,725-base-pair genome of Thermotoga maritima MSB8 contains 1,877 predicted coding regions, 1,014 (54%) of which have functional assignments and 863 (46%) of which are of unknown function. Genome analysis reveals numerous pathways involved in degradation of sugars and plant polysaccharides, and 108 genes that have orthologues only in the genomes of other thermophilic Eubacteria and Archaea. Of the Eubacteria sequenced to date, T. maritima has the highest percentage (24%) of genes that are most similar to archaeal genes. Eighty-one archaeal-like genes are clustered in 15 regions of the T. maritima genome that range in size from 4 to 20 kilobases. Conservation of gene order between T. maritima and Archaea in many of the clustered regions suggests that lateral gene transfer may have occurred between thermophilic Eubacteria and Archaea.

PubMed Disclaimer

Similar articles

See all similar articles

Cited by

See all "Cited by" articles

Publication types

Associated data